総説・解説等

The synthesis of mirror life, an organism composed entirely of the mirror-image counterparts of naturally occurring biomolecules, may be a topic for science fiction today but is suggested to be a reality in the future. Scientists called for strict preemptive regulation for the synthesis of mirror life due to concerns regarding biosecurity risks, such as the potential threat of mirror life to humans and non-human ecosystems. This perspective reports on the discussions held at two recent symposia in Japan, at the Japanese Society for Cell Synthesis Research (JSCSR) meeting and at the Biophysical Society of Japan (BSJ) annual meeting. Participants, including synthetic biologists, social scientists and artists, discussed the feasibility of the synthesis of mirror-image artificial self-replicating cells and the balance between the risks and benefits of this emerging technology. The discussions indicate that, while safety management is essential, a rational, evidence-based framework developed through open dialogue with society is crucial for the responsible advancement of mirror life research.

We have written the introduction to this special issue on responsible research and innovation (RRI) in the UK and Japan as a visitor's guide to an imaginary island holiday park to emphasize how we have centered the situatedness of practices that contribute to responsibility in science and technology. Our overarching argument is that RRI cannot be discussed as a program without foregrounding its location, and that RRI therefore needs “alternative practices”—heuristics that inspire adaptation in context—above “best practices” that might be exported from historic centers of investment to historically marginalized peripheries. We have also gravitated to experiment and play as strategies to find more space for intellectually rich, personally satisfying, and collectively enjoyable work amid pressures for STS researchers to take on rote service work under RRI mandates. We welcome you to the place—トピアtopia—that our collaboration has built and invite you to travel with us through the alternative practices we have sketched out here.

In the 2020 Prague Virtual Conference of the Society for Social Studies of Science (4S), Sharon Traweek was awarded the society’s John D. Bernal Prize jointly with Langdon Winner, for her distinguished contributions to the field of STS. In this essay responding to Traweek’s Bernal Lecture, I explore the continuing relevance of her work for Japan’s STS community. Even though this community has grown rapidly since the beginning of the 2000s, I argue in this essay that her work, produced more than three decades ago, encourages us today to reflect how we may want to relate ourselves to the local organization of science and the politics of epistemic authority in the country.