著書

During the past 70 years, a relationship between low-density lipoprotein cholesterol (LDL-C) and coronary heart disease (CHD) incidence has been established in many countries. Evidence of causality has been provided by the reduction of CHD risk with pharmacologic lowering of LDL-C. These findings have made it possible to develop risk assessment charts for CHD and to detect high-risk individuals for early intervention. However, a causal relation between LDL-C concentration and stroke, remains controversial.