In recent years, it has become clear that hypoxia-inducing factor (HIF) plays an important role in retinal diseases that cause blindness. 6 types of fish with HIF inhibitory activity have been screened out from the fish extracts in Shizuoka prefecture that have been collected and extracted at the Shizuoka Prefectural Fisheries and Marine Technology Research Institute. This year, from the obtained fish extracts, active substances were fractionated, purified, and structurally determined at the Fuculty of Agriculture, Shizuoka University. Then, we performed in vitro experiments and identified some of the active components at Laboratory of Photobiology, Keio University School of Medicine.
Applicable regions
Shizuoka prefecture
Implementation period
October, 2019 - present
Community and Regional Affairs category
Regional collaboration as research targets and implementation sites/research that aims to popularize region-specific issues
Related websites
Related agreements, etc.
Seeds creation research work centered on marine biotechnology
Cooperating institutions, etc.
Shizuoka Prefectural Research Institute of fishery and Marine
Fuculty of Agriculture, Shizuoka University
Campus
Shinanomachi
Person in charge
Toshihide Kurihara, MD/PhD
Inquiries
kurihara@z8.keio.jp