Presentations
YOKOGAWA Mariko
21-40 items (total 49)
2023.08
リン酸化および14-3-3ζの結合による転写因子FOXO3aの機能抑制機構の解明
- Speaker
- 榎本翔太，桑山知也，横川真梨子，中塚将一，河津光作，中村吏佐，木村友美，齋藤潤，佐谷秀行，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.08.31 - 2023.09.01
- Organizer
- 日本薬学会 物理系薬学部会
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- Conference Category
- Oral presentation (general)
2023.08
ALSの原因となるTDP-43沈殿を抑制するRNAの創製
- Speaker
- 西村錬，西田優理華，横川真梨子，坂上史佳，横田隆徳，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.08.31 - 2023.09.01
- Organizer
- 日本薬学会 物理系薬学部会
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Oral presentation (general)
2023.09
ALSの原因となるTDP-43の沈殿形成を抑制するRNAの探索
- Speaker
- 西田優理華，西村錬，横川真梨子，坂上史佳，横田隆徳，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.09.16 - 2023.09.16
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- Conference Category
- Poster presentation
2023.10
Structural basis of the inhibition of the Keap1-Nrf2 interaction by novel PPI inhibitors discovered by machine learning
- Conference Title
- [Conference Category Domestic presentation] Conference Title Kouji Kojima，Hanako Ishida，Ayaka Harada，Tomoki Yonezawa，Yugo Shimizu，Kazuyoshi Ikeda，Mariko Yokogawa，Masanori Osawa Dates 2023.10.23 - 2023.10.26
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Poster presentation
2023.11
NMR解析により得られたKeap1-Nrf2のPPI阻害化合物のKeap1結合の構造基盤
- Speaker
- 小島行人，石田英子，原田彩佳，米澤朋起，清水祐吾，池田和由，横川真梨子，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.11.07 - 2023.11.09
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Poster presentation
2023.11
14-3-3ζによる転写因子FOXO3aの阻害メカニズムの解明
- Speaker
- 榎本翔太，桑山知也，中塚将一，横川真梨子，河津光作，中村吏佐，木村友美，田辺幹雄，千田俊哉，齋藤潤，佐谷秀行，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.11.07 - 2023.11.09
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Oral presentation (general)
2023.12
Structural insights into the inhibitory mechanism of transcription factor FOXO3a by phosphorylation and 14-3-3ζ
- Speaker
- 榎本翔太，桑山知也，中塚将一，横川真梨子，河津光作，中村吏佐，木村友美，田辺幹雄，千田俊哉，齋藤潤，佐谷秀行，大澤匡範
- Conference Title
- Dates 2023.12.06 - 2023.12.08
- Invitation Status
- Without
- Conference Category
- Poster presentation
2023.12
Structural mechanism for the acceleration of the Caf1-dependent deadenylation of mRNA by BTG2
- Speaker
- 片岡奈緒，横川真梨子，石井裕一郎，城えりか，高嶋大翔，沢崎綾一，寒河江彪流，尾上耕一，星野真一，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.12.06 - 2023.12.08
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Poster presentation
2023.10
Discovery of the middle-sized compounds inhibiting the SARS-CoV-2 viral entry, using in silico approach and NMR analysis
- Speaker
- 横川 真梨子, 堀内 まほろ, 金一 駿希, 大竹 帝河, 米澤 朋起, 清水 祐吾, 池田 和由, 山 本 雄一朗, 酒井 祥太, 野口 耕司, 深澤 征義, 大澤 匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.10.23 - 2023.10.26
- Presentation Format
- Domestic presentation
- Conference Category
- Poster presentation
2023.11
NMR-based drug discovery of the entry inhibitor of SARS-CoV-2 that directly binds to SARS-CoV-2 spike protein
- Speaker
- 金一 駿希, 横川 真梨子, 堀内 まほろ,大竹 帝河, 米澤 朋起, 清水 祐吾, 池田 和由, 山 本 雄一朗, 酒井 祥太, 野口 耕司, 深澤 征義, 大澤 匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.11.07 - 2023.11.09
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Poster presentation
2023.11
NMR-based drug discovery of the entry inhibitor of SARS-CoV-2 that directly binds to hACE2
- Speaker
- 横川 真梨子, 堀内 まほろ, 金一 駿希, 大竹 帝河, 米澤 朋起, 清水 祐吾, 池田 和由, 山 本 雄一朗, 酒井 祥太, 野口 耕司, 深澤 征義, 大澤 匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.11.07 - 2023.11.09
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Poster presentation
2023.07
NMR-based drug design of the entry inhibitor of SARS-CoV-2 targeting the interaction between SARS-CoV-2 spike protein and hACE2
- Speaker
- 横川 真梨子, 堀内 まほろ, 金一 駿希, 大竹 帝河, 米澤 朋起, 清水 祐吾, 池田 和由, 山 本 雄一朗, 酒井 祥太, 野口 耕司, 深澤 征義, 大澤 匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.07.05 - 2023.07.07
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- Conference Category
- Poster presentation
Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail
- Speaker
- Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Conference Title
- [Conference Category International presentation] Conference Title International Council on Magnetic Resonance in Biological Systems（Venue Boston） Dates 2022.08.21 - 2022.08.25
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Oral presentation (general)
2022
Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail
- Speaker
- 寒河江彪流，横川真梨子，沢崎綾一，石井裕一郎，細田直，星野真一，今井駿輔，嶋田一夫，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2022.11.08 - 2022.11.10
- Presentation Format
- Domestic presentation
- Conference Category
- Oral presentation (general)
2022
Paip2 competitively dissociates PABPC1 from poly(A) by accessing RRM2 of the poly(A)-bound PABPC1
- Speaker
- Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Conference Title
- [Conference Category Domestic presentation] Dates 2022.06.07 - 2022.06.09
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Oral presentation (general)
2022.09
NMRによるPPI 阻害化合物と標的タンパク質との相互作用の構造生物学的解析とドラッグデザイン
- Speaker
- 小島行人，清水祐吾，米澤朋起，池田和由，原田彩佳，横川真梨子，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2022.09.12 - 2022.09.13
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Conference Category
- Oral presentation (general)
2022
Paip2A inhibits translation by competitively binding to the RNA recognition motifs of poly(A)-binding protein C1 and promoting its dissociation from the poly(A) tail
- Speaker
- Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
- Conference Title
- Dates 2022.07.20 - 2022.07.22
- Invitation Status
- Without
- Conference Category
- Poster presentation
2022.11
Structural insights into the inhibitory mechanism of transcription factor FOXO3a by 14-3-3ζ
- Speaker
- 桑山知也，中塚将一，横川真梨子，河津光作，中村吏佐， 木村友美，田辺幹雄，千田俊哉，齋藤潤，佐谷秀行，大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2022.11.08 - 2022.11.10
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- International Co-authorship
- No
- Conference Category
- Poster presentation
Structural basis for the inhibition mechanism of hepatitis B virus infection by oolonghomobisflavan C
- Speaker
- 石場 智彬, 横川 真梨子, 横田 旭美, 大澤 匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.03.25 - 2023.03.28
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- International Co-authorship
- No
- Conference Category
- Poster presentation
2023.03
COVID-19の原因となるタンパク質-タンパク質相互作用を標的とする合成中分子阻害剤のインシリコスクリーニング
- Speaker
- 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 野口耕司, 酒井祥太, 深澤征義, 横川真梨子, 大澤匡範
- Conference Title
- [Conference Category Domestic presentation] Dates 2023.03.25 - 2023.03.28
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- International Co-authorship
- No
- Conference Category
- Poster presentation