Keio University

Presentations

YOKOGAWA Mariko

1-20 items (total 49)
2025.12

Structural basis for BTG2-Caf1-dependent deadenylation regulated by dynamic interactions between poly(A) and PABPC1

Speaker
Nao Kataoka, Mariko Yokogawa, Yuichiro Ishii, Erika Shiro, Hiroka Takashima, Ryoichi Sawazaki, Takeru Sagae, Koichi Ogami, Shin-ichi Hoshino, Masanori Osawa
Conference Title
[Conference Category Domestic presentation] Dates 2025.12.03 - 2025.12.05
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation

Discovery of COVID-19 therapeutic seeds using angiotensin-converting enzyme 2 (ACE2) immobilized beads

Speaker
江川 奏, 齋藤 駿, 山本 瑞生, 横川 真梨子, 大澤 匡範, 荻 貴之, 荒井 緑
Conference Title
[Conference Category Domestic presentation] Dates 2025.03.26 - 2025.03.29
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Oral presentation (general)
2025.06

TDP-43の凝集を抑制するALS治療薬の創製とその作用機序の解明

Speaker
西村 錬, 西田 優理華, 八城 立樹, 坂上 史佳, 三浦 元輝, 横田 隆徳, 石田 英子, 横川 真梨子, 大澤 匡範
Conference Title
[Conference Category Domestic presentation] Dates 2025.06.18 - 2025.06.20
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2025.09

がんの増悪を引き起こすZBTB2によるHIF-1活性化機構の解明

Speaker
川﨑楽樹, 横川真梨子, 鈴木翔太, 寒河江彪流, 榎本翔太, 原田浩, 大澤匡範
Conference Title
[Conference Category Domestic presentation] Dates 2025.09.13 - 2025.09.13
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2025.09

ポリA 結合タンパク質PABPC1 と翻訳抑制因子Paip2 の結合様式の解明

Speaker
山越若菜, 横川真梨子, 加藤菜乃, 寒河江彪流, 石田英子, 細田直, 星野真一, 大澤匡範
Conference Title
[Conference Category Domestic presentation] Dates 2025.09.13 - 2025.09.13
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2025.10

Angiotensin-converting enzyme 2 (ACE2) 担持ビーズを用いた新型コロナウイルス感染症治療薬シードの探索

Speaker
江川 奏, 齋藤 駿, 山本 瑞生, 横川 真梨子, 大澤 匡範, 荻 貴之, 荒井 緑
Conference Title
[Conference Category Domestic presentation] Dates 2025.10 - 2025.10
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Poster presentation
2025.10

Sugar-binding characteristics of SARS-CoV-2 spike proteins

Speaker
Dai Hatakeyama, Yusuke Miki, Masaki Shoji, Shoji Ueki, Kentaro Yamaguchi, Katsuyuki Nakashima, Yoshiyuki Tanaka, Mariko Yokogawa, Masanori Osawa, Rina Hashimoto, Kazuo Takayama, Hiroshi Imagawa, Takashi Kuzuhara
Conference Title
[Conference Category International presentation] Conference Title ESWI Influenza Conference 2025 Dates 2025.10 - 2025.10
Invitation Status
Without
Presentation Format
International presentation
International Co-authorship
No
Conference Category
Poster presentation
2025.11

14-3-3ζ interacts with DNA-binding domain of FOXO3a and competitively dissociates DNA by dual-motif tethering

Speaker
Shota Enomoto, Tomoya Kuwayama, Shoichi Nakatsuka, Mariko Yokogawa, Kosaku Kawatsu, Risa Nakamura, Tomomi Kimura, Mikio Tanabe, Toshiya Senda, Jun Saito, Hideyuki Saya, Masanori Osawa
Conference Title
[Conference Category Domestic presentation] Dates 2025.11.26 - 2025.11.28
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2025.11

NMR化学シフト変化に基づく低親和性リガンドの結合様式推定手法の構築

Speaker
小島行人, 石田英子, 米澤朋起, 原田彩佳, 前川こひろ, 横川真梨子, 清水祐吾, 池田和由, 大澤匡範
Conference Title
[Conference Category Domestic presentation] Dates 2025.11.26 - 2025.11.28
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2025.11

ALS関連タンパク質TDP-43の凝集と核酸による抑制機構の解明

Speaker
西村 錬, 西田 優理華, 八城 立樹, 坂上 史佳, 三浦 元輝, 横田 隆徳, 石田 英子, 横川 真梨子, 大澤 匡範
Conference Title
[Conference Category Domestic presentation] Dates 2025.11.26 - 2025.11.28
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2025.11

新型コロナウイルスの侵入を阻害するタンパク質タンパク質相互作用阻害化合物の創製

Speaker
横川真梨子, 金一駿希, 堀内まほろ, 大竹帝河, 米澤朋起, 清水祐吾, 池田和由, 山本雄一朗, 酒井祥太, 清水芳実, 野口耕司, 深澤征義, 伊倉光彦, 大澤匡範
Conference Title
[Conference Category Domestic presentation] Dates 2025.11.26 - 2025.11.28
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
Conference Category
Oral presentation (general)
2024.05

INT-767の作用機序に基づいた胆汁酸誘導体による新規抗HBV薬の開発

Speaker
奥村彰規、荒井潤、池田和由、山下ユキコ、井口裕介、横川真梨子、梅澤一夫、宇根瑞穂、大澤匡範、伊藤清顕
Conference Title
[Conference Category Domestic presentation] Dates 2024.05.09 - 2024.05.11
Invitation Status
Without
Presentation Format
Domestic presentation
International Co-authorship
No
Conference Category
Symposium, workshop panel (public)
2024.09

Development of novel anti-HBV drugs based on AI technology using bile acid derivatives to inhibit HBV and NTCP binding

Speaker
Okumura A, Ikeda K, Arai J , Muraki Y , Nishimura S, Inden N, Yokogawa M, Yamashita Y, Iguchi Y, Ohashi H, Watashi K, Wakita T, Une M, Osawa M, Ito K
Conference Title
[Conference Category International presentation] Conference Title International HBV Meeting 2024 Dates 2024.09.11 - 2024.09.16
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2024.10

Angiotensin-converting enzyme 2 (ACE2) 担持ビーズを用いた 新型コロナウイルス感染症治療薬シードの探索

Speaker
江川 奏, 齋藤 駿, 山本 瑞生, 横川 真梨子, 大澤 匡範, 荻 貴之, 荒井 緑
Conference Title
[Conference Category Domestic presentation] Dates 2024.10.12 - 2024.10.13
Invitation Status
Without
Presentation Format
Domestic presentation
International Co-authorship
No
Conference Category
Poster presentation
2024.08

新規Keap1-Nrf2タンパク質間相互作用阻害剤とKeap1結合の構造基盤

Speaker
小島 行人, 石田 英子, 原田 彩佳, 米澤 朋起, 清水 祐吾, 池田 和由, 横川 真梨子, 大澤 匡範
Conference Title
[Conference Category Domestic presentation] Dates 2024.08.22 - 2024.08.23
Organizer
日本薬学会 物理系薬学部会
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Oral presentation (general)
Country
Japan
2024.08

BTG2によるCaf1依存的ポリA分解の促進機構の解明

Speaker
片岡 奈緒, 横川 真梨子, 石井 裕一郎, 城 えりか, 高嶋 大翔, 沢崎 綾一, 寒河江 彪流, 尾上 耕一, 星野 真一, 大澤 匡範
Conference Title
[Conference Category Domestic presentation] Dates 2024.08.22 - 2024.08.23
Organizer
日本薬学会 物理系薬学部会
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Oral presentation (general)
Country
Japan

14-3-3ζ Interacts with FOXO3a-DBD and Competitively Dissociates DNA through the Tethering Effects via Two Binding Motifs.

Speaker
Shota Enomoto, Tomoya Kuwayama, Shoichi Nakatsuka, Mariko Yokogawa, Kosaku Kawatsu, Risa Nakamura, Mikio Tanabe, Toshiya Senda, Jun Saitoh, Hideyuki Saya, Masanori Osawa
Conference Title
[Conference Category International presentation] Conference Title ICMRBS 2024 Dates 2024.08.18 - 2024.08.23
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
Country
Korea, Republic of

Discovery of the Middle-sized Compounds Inhibiting the SARS-CoV-2 Viral Entry, Using in Silico Approach and NMR Analysis

Speaker
Mariko Yokogawa, Shunki Kaneichi, Mahoro Horiuchi, Taiga Otake, Tomoki Yonezawa, Yugo Shimizu, Kazuyoshi Ikeda, Yuichiro Yamamoto, Shota Sakai, Yoshimi Shimizu, Kohji Noguchi, Masayoshi Fukasawa, Mitsuhiko Ikura, Masanori Osawa
Conference Title
[Conference Category International presentation] Conference Title ICMRBS 2024 Dates 2024.08.18 - 2024.08.23
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
Yes
Conference Category
Poster presentation
Country
Korea, Republic of
2023.09

HBV PreS1/NTCP相互作用に対する阻害剤簡易スクリーニング系の構築

Speaker
堀渕慶太,入間田早瑛,山本雄一朗,横川真梨子, 清水祐吾,米澤朋起,池田和由,浅見仁太,清水敏之,大戸梅治,深澤征義,,大澤匡範,野口耕司
Conference Title
[Conference Category Domestic presentation] Dates 2023.09.16 - 2023.09.16
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
Conference Category
Poster presentation
2023.11

タンパク質-タンパク質相互作用をターゲットとした感染阻害大環状物質の探索と構造活性相関解析

Speaker
米澤朋起,清水祐吾,池田和由,山本雄一朗,野口耕司,酒井祥太,深澤征義,横川真梨子,大澤匡範
Conference Title
[Conference Category Domestic presentation] Dates 2023.11.20 - 2023.11.21
Organizer
日本薬学会構造活性相関部会
Presentation Format
Domestic presentation
Conference Category
Oral presentation (general)