Furukawa, Yoshiaki
フルカワ ヨシアキ
Furukawa, Yoshiaki
Faculty of Science and Technology Department of Chemistry/ProfessorBasic Information
Specialty
Integrated Bio-metal Science, Bioinorganic Chemistry, Protein Science
Related Links
Researcher Number
40415287
Paper Review Qualification
Thesis Guide Qualification in the Graduate School of Science and Technology : Master/Doctor
Biography
Research experience
京都大学大学院 工学研究科分子工学専攻 日本学術振興会 特別研究員 (DC2)
Keio University Faculty of Science and Technology Department of Chemistry Associate Professor (Non-Tenured)
Keio University Faculty of Science and Technology Department of Chemistry Associate Professor
Research
Reseach overview
Intracellular dynamics of metal ions is known to be strictly regulated in their qualities as well as quantities, and proteins called "metallochaperones" are responsible for maintenance of the regulation. A purpose of our research is to decipher a mechanism that enables metalloproteins to receive specific metal ions from metallochaperones. Also, we are investigating a pathomechanism of neurodegenerative diseases that appear to be caused by breakdown of the intracellular metal dynamics.
Research Interests
- 蛋白質凝集・ミスフォールディング
- 金属シャペロン蛋白質
- 神経変性疾患
- 筋萎縮性側索硬化症
- 生体内亜鉛イオン
- 生体内銅イオン
- 必須微量元素
- SOD1
- Metalloprotein
- Neurodegenerative disease
- Intracellular copper transport
- Metallochaperone protein
- Amyotrophic lateral sclerosis
- Cu/Zn-superoxide dismutase
Research areas
Pharmaceutical analytical chemistry and physicochemistry
Functional biochemistry
Pathophysiologic neuroscience
Functional biochemistry