Keio University

Published papers

Simizu, Siro

101-118 items (total 118)

Exploitation of heparanase inhibitors from microbial metabolites using an efficient visual screening system

Author
Ishida K, Teruya T, Simizu S & Osada H.
Publication Title
Magazine name J. Antibiot. Start Page 136 - End Page 142 (Publication Date)2004)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Novel heparan sulfate mimetic compounds as antitumor agents

Author
Ishida K, Wierzba MK, Teruya T, Simizu S & Osada H.
Publication Title
Magazine name Chem. Biol. Start Page 367 - End Page 377 (Publication Date)2004)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Secretion of heparanase protein is regulated by glycosylation in human tumor cell lines

Author
Simizu S, Ishida K, Wierzba MK & Osada H.
Publication Title
Magazine name J. Biol. Chem. Start Page 2697 - End Page 2703 (Publication Date)2004)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions

Author
Kanoh N, Kumashiro S, Simizu S, Kondoh Y, Hatakeyama S, Tashiro H & Osada H.
Publication Title
Magazine name Angew. Chem. Int. Ed. Start Page 5584 - End Page 5587 (Publication Date)2003)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Apoptosis-inducing properties of ent-kaurene-type diterpenoids from the liverwort Jungermannia truncata

Author
Nagashima F, Kondoh M, Kawase M, Simizu S, Osada H, Fujii M, Watanabe Y, Sato M & Asakawa Y.
Publication Title
Magazine name Planta Med. Start Page 377 - End Page 379 (Publication Date)2003)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)

Transmembrane domain of Bcl-2 is required for inhibition of ceramide synthesis, but not cytochrome c release in the pathway of inostamycin-induced apoptosis

Author
Kawatani M, Uchi M, Simizu S, Osada H & Imoto M.
Publication Title
Magazine name Exp. Cell Res. Start Page 57 - End Page 66 (Publication Date)2003)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Expression of heparanase in human tumor cell lines and human head and neck tumors

Author
Simizu S, Ishida K, Wierzba MK, Sato T-A & Osada H.
Publication Title
Magazine name Cancer Lett. Start Page 83 - End Page 89 (Publication Date)2003)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Bcl-2-independent induction of apoptosis by neuropeptide receptor antagonist in human small cell lung carcinoma cells

Author
Matsumoto Y, Kawatani M, Simizu S, Tanaka T, Takada M & Imoto M.
Publication Title
Magazine name Anticancer Res. Start Page 3123 - End Page 3129 (Publication Date)2000)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Involvement of protein kinase C-regulated ceramide generation in inostamycin-induced apoptosis

Author
Kawatani M, Simizu S, Osada H, Takada M, Arber N & Imoto M.
Publication Title
Magazine name Exp. Cell Res. Start Page 389 - End Page 397 (Publication Date)2000)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Mutations in the Plk gene lead to instability of Plk protein in human tumour cell lines

Author
Simizu S & Osada H.
Publication Title
Magazine name Nature Cell Biol. Start Page 852 - End Page 854 (Publication Date)2000)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Bcl-2 inhibits calcineurin-mediated Fas ligand expression in antitumor drug-treated baby hamster kidney cells

Author
Simizu S, Shibasaki F & Osada H.
Publication Title
Magazine name Jpn. J. Cancer Res. Start Page 706 - End Page 714 (Publication Date)2000)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs

Author
Simizu S, Takada M, Umezawa K & Imoto M.
Publication Title
Magazine name J. Biol. Chem. Start Page 26900 - End Page 26907 (Publication Date)1998)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Potentiation of paclitaxel cytotoxicity by inostamycin in human small cell lung carcinoma, Ms-1 cells

Author
Simizu S, Tanabe K, Tashiro E, Takada M, Umezawa K & Imoto M.
Publication Title
Magazine name Jpn. J. Cancer Res. Start Page 970 - End Page 976 (Publication Date)1998)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Caspase-3 activation is not responsible for vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in human small cell lung carcinoma Ms-1 cells

Author
Tashiro E, Simizu S, Takada M, Umezawa K & Imoto M.
Publication Title
Magazine name Jpn. J. Cancer Res. Start Page 940 - End Page 946 (Publication Date)1998)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Inhibition of cyclin D1 expression and induction of apoptosis by inostamycin in small cell lung carcinoma cells

Author
Imoto M, Tanabe K, Simizu S, Tashiro E, Takada M & Umezawa K.
Publication Title
Magazine name Jpn. J. Cancer Res. Start Page 315 - End Page 322 (Publication Date)1998)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Induction of hydrogen peroxide production and Bax expression by caspase-3(-like) proteases in tyrosine kinase inhibitor-induced apoptosis in human small cell lung carcinoma cells

Author
Simizu S, Umezawa K, Takada M, Arber N & Imoto M.
Publication Title
Magazine name Exp. Cell Res. Start Page 197 - End Page 203 (Publication Date)1998)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Involvement of hydrogen peroxide production in erbstatin-induced apoptosis in human small cell lung carcinoma cells

Author
Simizu S, Imoto M, Masuda N, Takada M & Umezawa K.
Publication Title
Magazine name Cancer Res. Start Page 4978 - End Page 4982 (Publication Date)1996)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Induction of apoptosis by erbstatin in mouse leukemia L1210 cells

Author
Simizu S, Imoto M & Umezawa K.
Publication Title
Magazine name Biosci. Biotechnol. Biochem. Start Page 1549 - End Page 1552 (Publication Date)1994)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With