Keio University

Published papers

Simizu, Siro

81-100 items (total 118)

Cleavable linker for photo-cross-linked small-molecule affinity matrix

Author
Kanoh N, Takayama H, Honda K, Moriya T, Teruya T, Simizu S, Osada H & Iwabuchi Y.
Publication Title
Magazine name Bioconjugate Chem. Start Page 182 - End Page 186 (Publication Date)2010)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Deamino-hydroxy-phoslactomycin B, a biosynthetic precursor of phoslactomycin, induces myeloid differentiation in HL-60 cells

Author
Simizu S, Teruya T, Nogawa T, Aono H, Ueki M, Uramoto M, Kobayashi Y & Osada H.
Publication Title
Magazine name Biochem. Biophys. Res. Commun. Start Page 406 - End Page 410 (Publication Date)2009)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Structure-affinity relationship study of bleomycins and Shble protein by use of a chemical array

Author
Miyazaki I, Okumura H, Simizu S, Takahashi Y, Kanoh N, Muraoka Y, Nonomura Y & Osada H.
Publication Title
Magazine name ChemBioChem Start Page 845 - End Page 852 (Publication Date)2009)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

On-chip fragment-based approach for discovery of high-affinity bivalent inhibitors

Author
Miyazaki I, Simizu S, Ishida K & Osada H.
Publication Title
Magazine name ChemBioChem Start Page 838 - End Page 843 (Publication Date)2009)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

RECK negatively regulates matrix metalloproteinase-9 transcription

Author
Takagi S, Simizu S & Osada H.
Publication Title
Magazine name Cancer Res. Start Page 1502 - End Page 1508 (Publication Date)2009)
Role
Corresponding Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

A cell-based screening to detect inhibitors of BRAF signaling pathway

Author
Asami Y, Mori M, Koshino H, Sekiyama Y, Teruya T, Simizu S, Usui T & Osada H.
Publication Title
Magazine name J. Antibiot. Start Page 105 - End Page 107 (Publication Date)2009)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Polo-like kinase 1 phosphorylates and regulates Bcl-xL during pironetin-induced apoptosis

Author
Tamura Y, Simizu S, Muroi M, Takagi S, Kawatani M, Watanabe N & Osada H.
Publication Title
Magazine name Oncogene Start Page 107 - End Page 116 (Publication Date)2009)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Robust and systematic drug screening method using chemical arrays and the protein library: identification of novel inhibitors of carbonic anhydrase II

Author
Miyazaki I, Simizu S, Ichimiya H, Kawatani M & Osada H.
Publication Title
Magazine name Biosci. Biotechnol. Biochem. Start Page 2739 - End Page 2749 (Publication Date)2008)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Requirement of the conserved, hydrophobic C-terminus region for the activation of heparanase

Author
Lai NS, Simizu S, Morisaki D, Muroi M & Osada H.
Publication Title
Magazine name Exp. Cell Res. Start Page 2834 - End Page 2845 (Publication Date)2008)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Involvement of disulfide bond formation in the activation of heparanase

Author
Simizu S, Suzuki T, Muroi M, Lai NS, Takagi S, Dohmae N & Osada H.
Publication Title
Magazine name Cancer Res. Start Page 7841 - End Page 7849 (Publication Date)2007)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Synthesis of (+)-vinblastine and its analogues

Author
Miyazaki T, Yokoshima S, Simizu S, Osada H, Tokuyama H & Fukuyama T.
Publication Title
Magazine name Org. Lett. Start Page 4737 - End Page 4740 (Publication Date)2007)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Photo-cross-linked small-molecule microarrays as chemical genomic tools for dissecting protein-ligand interactions

Author
Kanoh N, Asami A, Kawatani M, Honda K, Kumashiro S, Takayama H, Simizu S, Amemiya T, Kondoh Y, Hatakeyama S, Tsuganezawa K, Utata R, Tanaka A, Yokoyama S, Tashiro H & Osada H.
Publication Title
Magazine name Chem. Asian J. Start Page 789 - End Page 797 (Publication Date)2006)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

RECK-mediated suppression of tumor cell invasion is regulated by glycosylation in human tumor cell lines

Author
Simizu S, Takagi S, Tamura Y & Osada H.
Publication Title
Magazine name Cancer Res. Start Page 7455 - End Page 7461 (Publication Date)2005)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Photo-cross-linked small-molecule affinity matrix for facilitating forward and reverse chemical genetics

Author
Kanoh N, Honda K, Simizu S, Muroi M & Osada H.
Publication Title
Magazine name Angew. Chem. Int. Ed. Start Page 3559 - End Page 3562 (Publication Date)2005)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells

Author
Teruya T, Simizu S, Kanoh N & Osada H.
Publication Title
Magazine name FEBS Lett. Start Page 2463 - End Page 2468 (Publication Date)2005)
Role
Corresponding Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Structure-based design of a selective heparanase inhibitor as an antimetastatic agent

Author
Ishida K, Hirai G, Murakami K, Teruya T, Simizu S, Sodeoka M & Osada H.
Publication Title
Magazine name Mol. Cancer Ther. Start Page 1069 - End Page 1077 (Publication Date)2004)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria

Author
Tamura Y, Simizu S & Osada H.
Publication Title
Magazine name FEBS Lett. Start Page 249 - End Page 255 (Publication Date)2004)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Kaurene diterpene induces apoptosis in human leukemia cells partly through a caspase-8-dependent pathway

Author
Kondoh M, Suzuki I, Sato M, Nagashima F, Simizu S, Harada M, Fujii M, Osada H, Asakawa Y & Watanabe Y.
Publication Title
Magazine name J. Pharmacol. Exp. Ther. Start Page 115 - End Page 122 (Publication Date)2004)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Rational design and synthesis of novel heparan sulfate mimetic compounds as antiadhesive agents

Author
Ishida K, Simizu S, Teruya T, Wierzba MK & Osada H.
Publication Title
Magazine name Bioorg. Med. Chem. Lett. Start Page 2505 - End Page 2509 (Publication Date)2004)
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With

Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance

Author
Simizu S, Tamura Y & Osada H.
Publication Title
Magazine name Cancer Sci. Start Page 266 - End Page 270 (Publication Date)2004)
Role
First Author
Authorship Category
Joint Work
Publication Category
Research paper (scientific journal)
Peer-review Status
With