Keio University
1-20 items (total 31)
2025.11

Single-Cell Atlas of Wnt/β-Catenin-Driven Trophoblast Stem Cell Differentiation

Speaker
Takuro Ishinabe,Saki Noguchi, Natsuki Suganuma, Tomohiro Nishimura, Toshiaki Tsuchitani, Masatoshi Tomi.
Conference Title
[Conference Category International presentation] Conference Title The Early-Life Nexus: Molecular Keys to Health and Disease Dates 2025.11 - 2025.11
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
Yes
Conference Category
Poster presentation
2025.11

ヒト栄養膜幹細胞由来胎盤バリアモデルを用いたプロピオン酸透過機構の解析

Speaker
登美斉俊,緑川凜,土谷聡耀,堀武志,西村友宏,梶弘和,野口幸希.
Conference Title
[Conference Category Domestic presentation] Dates 2025.11 - 2025.11
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
Yes
Conference Category
Poster presentation
2025.11

マウス胎盤MFSD2Aが胎仔へのドコサヘキサエン酸輸送に与える影響

Speaker
石井あみ,野口幸希,関瑞生,関誠悟,山本元輝,定村龍太,赤沼伸乙,河野早弥賀,盛武浩,細谷 健一,土谷聡耀,西村友宏,登美斉俊.
Conference Title
[Conference Category Domestic presentation] Dates 2025.11 - 2025.11
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
Yes
Conference Category
Poster presentation
2025.12

Single-Cell Transcriptomic Analysis of Wnt/β-Catenin-mediated Differentiation Pathways in Mouse Trophoblast Stem Cells

Speaker
Takuro Ishinabe, Saki Noguchi , Natsuki Suganuma , Tomohiro Nishimura ,Toshiaki Tsuchitani , Masatoshi Tomi .
Conference Title
[Conference Category International presentation] Conference Title Asian Federation for Pharmaceutical Sciences Conference 2025 Dates 2025.12 - 2025.12
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2025.12

Identification of syncytiotrophoblast-specific transporter genes and their protein expression in mouse placenta

Speaker
Kurumi Inagaki, Saki Noguchi, Ryusei Takei, Takuro Ishinabe, Tomohiro Nishimura, Toshiaki Tsuchitani, Masatoshi Tomi
Conference Title
[Conference Category International presentation] Conference Title Asian Federation for Pharmaceutical Sciences Conference 2025 Dates 2025.12 - 2025.12
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2026.03

MCT1はヒト胎盤バリアモデルにおいてプロピオン酸の双方向輸送を促進するが、MCT4は促進しない。

Speaker
山本耕平, 緑川凜, 土谷聡耀, 野口幸希, 堀武志, 梶弘和, 登美斉俊.
Conference Title
[Conference Category Domestic presentation] Dates 2026.03 - 2026.03
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
Yes
Conference Category
Oral presentation (general)
2024.06

In vitro の薬理学的パラメータ (Kd, Ki など) から有効投与量, 有効血中濃度はどの程度推定できるのか?

Speaker
土谷聡耀.
Conference Title
[Conference Category Domestic presentation] Dates 2024.06 - 2024.06
Invitation Status
With
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2024.09

テルミサルタンの非線形動態解析:肝 OATP1B3 取り込みと薬理標的への結合の飽和の関与.

Speaker
土谷聡耀.
Conference Title
[Conference Category Domestic presentation] Dates 2024.09 - 2024.09
Invitation Status
With
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2025.02

Mechanistic pharmacokinetics modeling in the era of democratized drug discovery.

Speaker
土谷聡耀.
Conference Title
[Conference Category Domestic presentation] Dates 2025.02 - 2025.02
Invitation Status
With
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2024.07

Management of Drug-Drug/Disease-Interaction of IV Drug based on the Clearance Concept.

Speaker
Toshiaki Tsuchitani
Conference Title
[Conference Category International presentation] Conference Title 2024 Forbidden City International Pharmacist Conference Dates 2024.07 - 2024.07
Invitation Status
With
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2024.07

Understanding the Relationship of Trough Concentration and AUC based on the Clearance Concept.

Speaker
Toshiaki Tsuchitani
Conference Title
[Conference Category International presentation] Conference Title 2024 Forbidden City International Pharmacist Conference Dates 2024.07 - 2024.07
Invitation Status
With
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2024.09

Trends in in vitro potency and PK parameters; Can therapeutic dose be estimated from in vitro Ki?.

Speaker
Tsuchitani T, Kato M, Tomaru A, Tomi M, Sugiyama Y.
Conference Title
[Conference Category International presentation] Conference Title 26th North American ISSX and 39th JSSX Meeting Dates 2024.09 - 2024.09
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Poster presentation
2025.05

RPMI 2650 細胞株の膜透過性と鼻粘膜吸収率との相関性解析.

Speaker
森田時生, 土谷聡耀, 吉田寛幸, 富田奈緒美, 佐藤陽治.
Conference Title
[Conference Category Domestic presentation] Dates 2025.05.22 - 2025.05.24
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Poster presentation
2025.05

臨床データに基づいたOCT2介在性薬物間相互作用予測の精緻化.

Speaker
楠原洋之, 小石川知生, 友田有加菜, 土谷聡耀, 杉山雄一.
Conference Title
[Conference Category Domestic presentation] Dates 2025.05.22 - 2025.05.24
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Poster presentation
2025.07

PBPKモデル解析によって非線形薬物動態のメカニズムを理解しバイオアベイラビリティを推定する方法とは?.

Speaker
土谷聡耀.
Conference Title
[Conference Category Domestic presentation] Dates 2025.07 - 2025.07
Invitation Status
With
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2025.10

非線形条件下でのバイオアベイラビリティおよびそのメカニズムの推定方法.

Speaker
土谷聡耀.
Conference Title
[Conference Category Domestic presentation] Dates 2025.10 - 2025.10
Invitation Status
With
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2025.06

Integrating Non-Compartmental Analysis and PBPK Modeling: How to Understand Nonlinear Pharmacokinetic Mechanisms and Approximate Bioavailability Under Nonlinear Conditions.

Speaker
Toshiaki Tsuchitani
Conference Title
[Conference Category Domestic presentation] Conference Title 2025 Shanghai International Symposium: the Predictive ADMET Dates 2025.06 - 2025.06
Invitation Status
With
Presentation Format
Domestic presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2025.10

Tracing Professor Sugiyama’s Research on Albumin-Mediated Uptake: What Lies Ahead for Us?.

Speaker
Toshiaki Tsuchitani
Conference Title
[Conference Category Domestic presentation] Dates 2025.10 - 2025.10
Invitation Status
With
Presentation Format
Domestic presentation
Language of Publication
Japanese
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2026.02

Characterizing Apixaban Pharmacokinetics via PBPK Modeling: The Critical Roles of Biliary Secretion and Enterohepatic Circulation in Humans.

Speaker
Toshiaki Tsuchitani
Conference Title
[Conference Category International presentation] Conference Title Focus on Pharmacology Virtual Series: Current Advances in Drug Metabolism: PBPK Modeling for Human Drug Disposition: From Mechanistic Insights to Clinical Dosing Dates 2026.02 - 2026.02
Invitation Status
With
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Oral presentation (invited, special)
2025.06

Methylmalonic acid transport via organic anion transporters and effect of the inhibitor on its renal concentration

Speaker
Koki Isobe, Saki Noguchi, Yukiko Nakada, Saori Kobayashi, Toshiaki Tsuchitani Masatoshi Tomi.
Conference Title
[Conference Category International presentation] Conference Title The 4th Korea-Japan Young Scientists Workshop on Pharmaceutics Dates 2025.06 - 2025.06
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
International Co-authorship
No
Conference Category
Oral presentation (general)