Published papers
Imaoka, Ayuko
1-20 items (total 44)
Genetic polymorphisms of OATP1B1 influence the inhibitory potency of inhibitors and their pre-incubation effect.
- Author
- Tsujii K, Hirano T, Tanino M, Imaoka A, Akiyoshi T, Ohtani H.
- Publication Title
- Magazine name Scientific Reports (Publication Date）2026）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Effects of N-glycosylation on the transport kinetics of organic anion transporting polypeptide (OATP) 1B1.
- Author
- Tanino M, Tsujii K, Kataoka H, Takahashi R, Imaoka A, Akiyoshi T, Ohtani H.
- Publication Title
- Magazine name Biochimica et Biophysica Acta (BBA) - Biomembranes Volume 1868(Issue 2) Start Page 184509 (Publication Date）2026）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Stoichiometric transport of estrone 3-sulfate among genetic variants of OATP1A2 and OATP2B1 and structural analysis by molecular dynamics simulation: Impairment of gating mechanism in the unstable inward-open conformation of OATP2B1 (Asp215Val) significantly suppress the transport activity.
- Author
- Takeshi Akiyoshi, Arun Kumar Tonduru, Hiroki Kataoka, Tokio Morita, Kodai Yajima, Ayuko Imaoka, Kazuhiro Katayama, Prasanthi Medarametla, Yasuo Uchida, Antti Poso, Hisakazu Ohtani, Tetsuya Terasaki
- Publication Title
- Magazine name Drug Metab Dispos. Volume 53(Issue 12) Start Page 100198 (Publication Date）2025/12）
- Authorship Category
- Joint Work
- Peer-review Status
- With
Inhibition kinetics of citrus jabara juice and its components on CYP2C9 activity.
- Author
- Koinuma K, Morita T, Uekusa Y, Kikuchi H, Imaoka A, Akiyoshi T, Ohtani H.
- Publication Title
- Magazine name J Pharm Sci. Volume 114(Issue 11) Start Page 103983 (Publication Date）2025/09）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Comparative analysis of the single-molecule transport kinetics of OATP1B1 genetic variants.
- Author
- Tsujii K, Yajima K, Akiyoshi T, Sakamoto K, Suzuki Y, Oka T, Imaoka A, Yamamura H, Kurokawa J, Ohtani H.
- Publication Title
- Magazine name J Pharmacol Sci. Volume 158(Issue 3) Start Page 166 - End Page 171 (Publication Date）2025/07）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Kinetics of the inhibition of CYP3A4 and CYP2C19 activity by jabara juice and identification of the responsible inhibitory components.
- Author
- Koinuma K, Noto K, Morita T, Uekusa Y, Kikuchi H, Shimoji M, Seki H, Yamazaki H, Guengerich FP, Nakamura K, Yamamoto K, Imaoka A, Akiyoshi T, Ohtani H.
- Publication Title
- Magazine name J Pharm Sci. Volume 114(Issue 2) Start Page 849 - End Page 856 (Publication Date）2025）
- Authorship Category
- Joint Work
- Peer-review Status
- With
The effect of organic solvents on the in vitro transport activity of three OATP isoforms.
- Author
- Saito R, Akiyoshi T, Tsujii K, Takahashi R, Kataoka H, Imaoka A, Ohtani H.
- Publication Title
- Magazine name Toxicology in Vitro (Publication Date）2025）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
The Effects of N-Glycosylation on the Expression and Transport Activity of OATP1A2 and OATP2B1.
- Author
- Hiroki Kataoka, Takeshi Akiyoshi, Yasuo Uchida, Ayuko Imaoka, Tetsuya Terasaki, Hisakazu Ohtani
- Publication Title
- Magazine name J Pharm Sci. Volume 113(Issue 5) Start Page 1376 - End Page 1384 (Publication Date）2024）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Determination of single-molecule transport activity of OATP2B1 by measuring the number of transporter molecules using electrophysiological approach.
- Author
- Yajima K, Akiyoshi T, Sakamoto K, Suzuki Y, Oka T, Imaoka A, Yamamura H, Kurokawa J, Ohtani H.
- Publication Title
- Magazine name J Pharmacol Sci. Volume 153(Issue 3) Start Page 153 - End Page 160 (Publication Date）2023）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
The effects of jabara juice on the intestinal permeation of fexofenadine.
- Author
- Han H, Akiyoshi T, Morita T, Tsuchitani T, Nabeta M, Yajima K, Imaoka A, Ohtani H.
- Publication Title
- Magazine name Biol Pharm Bull. Volume 46(Issue 12) Start Page 1745 - End Page 1752 (Publication Date）2023）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
The influence of temperature on the metabolic activity of CYP2C9, CYP2C19, and CYP3A4 genetic variants in vitro.
- Author
- Kojima M, Machida K, Cho S, Watanabe D, Seki H, Shimoji M, Imaoka A, Yamazaki H, Guengerich FP, Nakamura K, Yamamoto K, Akiyoshi T, Ohtani H.
- Publication Title
- Magazine name Xenobiotica. Volume 53(Issue 5) Start Page 357 - End Page 365 (Publication Date）2023）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Irinotecan-induced gastrointestinal damage alters the expression of peptide transporter 1 and absorption of cephalexin in rats.
- Author
- Imaoka A, Hattori T, Akiyoshi T, Ohtani H.
- Publication Title
- Magazine name Biopharm Drug Dispos. Volume 44(Issue 5) Start Page 372 - End Page 379 (Publication Date）2023）
- Role
- First Author
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Mechanistic bottom-up estimation of passive drug absorption from the gastrointestinal tract--Comparison among primary cultured human intestinal cells, Caco-2 cells, artificial membrane, and animal scale-up-.
- Author
- Tsuchitani T, Akiyoshi T, Imaoka A, Ohtani H.
- Publication Title
- Magazine name Int J Clin Pharmacol Ther. Volume 60(Issue 5) Start Page 217 - End Page 224 (Publication Date）2022）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants.
- Author
- Han H, Akiyoshi T, Morita T, Kataoka H, Katayama K, Yajima K, Imaoka A, Ohtani H.
- Publication Title
- Magazine name Drug Metab Pharmacokinet. (Publication Date）2022）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.
- Author
- Araki N, Morita T, Akiyoshi T, Kataoka H, Yajima K, Katayama K, Imaoka A, Ohtani H.
- Publication Title
- Magazine name Drug Metab Pharmacokinet. Start Page 100464 (Publication Date）2022）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Prediction of the extent and variation of grapefruit juice-drug interactions from the pharmacokinetic profile in the absence of grapefruit juice.
- Author
- Kogure N, Akiyoshi T, Imaoka A, Ohtani H
- Publication Title
- Magazine name Biopharmaceutics & Drug Disposition Start Page 373 - End Page 381 (Publication Date）2014/06）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
Decrease in ciprofloxacin absorption by polyvalent metal cations is not fully attributable to chelation or adsorption.
- Author
- Imaoka A, Hattori M, Akiyoshi T, Ohtani H.
- Publication Title
- Magazine name Drug Metabolism and Pharmacokinetics Volume 29(Issue 5) Start Page 414 - End Page 418 (Publication Date）2014/10）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
常用量以下の曝露量における全身性副作用の用量依存性の推定
- Author
- 三井梨恵子, 秋好健志, 今岡鮎子, 望月眞弓, 大谷壽一.
- Publication Title
- Volume 17(Issue 2) Start Page 77 - End Page 86 (Publication Date）2015）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
インターネットオークションでの違法な医薬品取引と主催者による監視、削除の実態
- Author
- 大谷壽一, 今岡鮎子, 秋好健志.
- Publication Title
- Volume 135(Issue 3) Start Page 529 - End Page 534 (Publication Date）2015）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With
In silico evaluation of warfarin-bucolome therapy.
- Author
- Ohtani H, Hakoda R, Imaoka A, Akiyoshi T
- Publication Title
- Magazine name Biopharmaceutics & Drug Disposition Start Page 232 - End Page 242 (Publication Date）2016）
- Authorship Category
- Joint Work
- Publication Category
- Research paper (scientific journal)
- Peer-review Status
- With