Presentations
Yoshimoto, Keiko
1-20 items (total 29)
Possible involvement of the voltage-gated sodium channel 1.7 in activation of BAFF signaling in monocytes of patients with primary Sjögren’s syndrome.
- Speaker
- Keiko Yoshimoto, Katsuya Suzuki, Yumi Ikeda, Eriko Takei, Tsutomu Takeuchi
- Conference Title
- [Conference Category Domestic presentation] Conference Title The 50th annual meeting of Japanese Society for Immunology Dates 2021.12.09 - 2021.12.09
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
Signal transduction via BAFF receptor, BR3, is involved in activation of monocytes through NF-kB pathways in primary Sjögren’s syndrome.
- Speaker
- Keiko Yoshimoto, Katsuya Suzuki, Yumi Ikeda, Eriko Takei, Tsutomu Takeuchi
- Conference Title
- [Conference Category International presentation] Conference Title APLAR 2021 Dates 2021.08.28 - 2021.08.28
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Oral presentation (general)
The crosstalk between BAFF-signaling and sodium channel is involved in activation of monocytes of patients with primary Sjogren’s syndrome.
- Speaker
- Keiko Yoshimoto, Katsuya Suzuki, Yumi Ikeda, Eriko Takei, Tsutomu Takeuchi
- Conference Title
- [Conference Category Domestic presentation] Dates 2021.04 - 2021.04
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- Conference Category
- Oral presentation (general)
Possible involvement of Fractalkine/CX3CR1 axis in peripheral CD14++CD16+ monocytes in disease development of patients with systemic lupus erythematosus.
- Speaker
- Keiko Yoshimoto, Katsuya Suzuki, Noriyasu Seki, Shuntaro Saito, Jun Kikuchi, Tsutomu Takeuchi
- Conference Title
- [Conference Category International presentation] Conference Title ACR 2020 Dates 2020.11 - 2020.11
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Oral presentation (general)
Elevated expression of BAFF receptor, BR3, in peripheral monocytes is involved in B cell activation and clinical features of patients with primary Sjögren’s syndrome.
- Speaker
- Keiko Yoshimoto, Katsuya Suzuki, Eriko Takei, Yumi Ikeda, Tsutomu Takeuchi
- Conference Title
- [Conference Category Domestic presentation] Dates 2020.08 - 2020.08
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- Conference Category
- Oral presentation (general)
Elevated expression of BAFF-receptor in peripheral monocytes promotes B cell activation and correlates with clinical manifestations of primary Sjogren’s syndrome.
- Speaker
- Keiko Yoshimoto, Katsuya Suzuki, Yumi Ikeda, Eriko Takei, Tsutomu Takeuchi
- Conference Title
- [Conference Category International presentation] Conference Title EULAR 2019 Dates 2019.06 - 2019.06
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Oral presentation (general)
Innovative drug discovery for autoimmune diseases aiming at BAFF signaling pathway.
- Speaker
- Keiko Yoshimoto, Katsuya Suzuki, Noriyasu Seki, Kunio Sugahara, Kenji Chiba, Tsutomu Takeuchi
- Conference Title
- [Conference Category International presentation] Conference Title Immunology 2019 Dates 2019.05 - 2019.05
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Oral presentation (general)
Elevated expression levels of the voltage-gated sodium channel 1.7 and BAFF receptor in peripheral monocytes contribute to activation of monocytes of patients with primary Sjögren’s syndrome.
- Speaker
- Keiko Yoshimoto, Yumi Ikeda, Katsuya Suzuki, Tsutomu Takeuchi
- Conference Title
- [Conference Category International presentation] Conference Title Immunology 2019(Venue San Diego, California, U.S.A.) Dates 2019.05 - 2019.05
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
A low molecular weight BAFF signaling inhibitor reduces production of autoantibody and suppresses infiltration of B cells into the organs in autoimmune model mice.
- Speaker
- Keiko Yoshimoto, Katsuya Suzuki, Noriyasu Seki, Kunio Sugahara, Kenji Chiba, Tsutomu Takeuchi
- Conference Title
- [Conference Category Domestic presentation] Conference Title The 47th annual meeting of Japanese Society for Immunology Dates 2018.12 - 2018.12
- Invitation Status
- Without
- Presentation Format
- Domestic presentation
- Language of Publication
- English
- Conference Category
- Oral presentation (general)
Reduced expression of CX3CR1 in peripheral CD14++CD16+ monocytes is a novel feature of patients with systemic lupus erythematosus.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title ACR/ARHP Annual Meeting 2018 Dates 2018.10.22 - 2018.10.22
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
Localization of the voltage-gated sodium channel 1.7 in peripheral monocytes contributes to activation of BAFF signaling in monocytes of patients with primary Sjögren’s syndrome.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title ACR/ARHP Annual Meeting 2018 Dates 2018.10.21 - 2018.10.21
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Oral presentation (general)
BAFFシグナルを標的とした低分子化合物を用いたシェーグレン症候群治療薬創製への試み
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category Domestic presentation] Dates 2018.09.14 - 2018.09.14
- Invitation Status
- With
- Presentation Format
- Domestic presentation
- Language of Publication
- Japanese
- Conference Category
- Symposium, workshop panel (nominated)
Possible involvement of BAFF and matrixmetalloproteinase-9 in the activation of monocytes of patients with primary Sjögren’s syndrome.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title EULAR 2018 Dates 2018.06.15 - 2018.06.15
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
Elevated reactivity of CD38highIgD+ B cells against BAFF contributes to IgG overproduction in patients with primary Sjögren’s syndrome.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title EULAR 2018 Dates 2018.06.14 - 2018.06.14
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
A low molecular weight BAFF signaling inhibitor, BIK-13, ameliorates B cell activation in vitro and in vivo autoimmune models and consequently suppresses production of IgG and cytokines.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title EULAR 2018 Dates 2018.06.13 - 2018.06.13
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Oral presentation (general)
A Low molecular weight BAFF receptor antagonist inhibits differentiation of human peripheral B cells into plasma blasts/plasma cells in vitro.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title IMMUNOLOGY 2018 Dates 2018.05.07 - 2018.05.07
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
Low molecular weight BAFF receptor antagonists restrain infiltration of B cells into organs of autoimmune model mice by suppressing B cell activation.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title ACR/ARHP Annual Meeting 2017 Dates 2017.11 - 2017.11
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
Inhibition of BAFF binding to its receptor, BR3, with low molecular weight compounds results in suppression of activation of monocytes and B cells in vitro and in vivo model of autoimmune diseases.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title IMMUNOLOGY 2017 Dates 2017.05 - 2017.05
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
BAFF receptor antagonists suppress differentiation of B cells in vitro and are drug candidates for primary Sjögren’s syndrome.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title ACR/ARHP Annual Meeting 2016 Dates 2016.11 - 2016.11
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation
Low molecular weight compounds which inhibit BAFF binding to its receptor, BR3, suppress activation of monocytes.
- Speaker
- Yoshimoto Keiko
- Conference Title
- [Conference Category International presentation] Conference Title IMMUNOLOGY 2016 Dates 2016.05 - 2016.05
- Invitation Status
- Without
- Presentation Format
- International presentation
- Language of Publication
- English
- Conference Category
- Poster presentation