Keio University

Presentations

Yoshimoto, Keiko

1-20 items (total 29)

Possible involvement of the voltage-gated sodium channel 1.7 in activation of BAFF signaling in monocytes of patients with primary Sjögren’s syndrome.

Speaker
Keiko Yoshimoto, Katsuya Suzuki, Yumi Ikeda, Eriko Takei, Tsutomu Takeuchi
Conference Title
[Conference Category Domestic presentation] Conference Title The 50th annual meeting of Japanese Society for Immunology Dates 2021.12.09 - 2021.12.09
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
Conference Category
Poster presentation

Signal transduction via BAFF receptor, BR3, is involved in activation of monocytes through NF-kB pathways in primary Sjögren’s syndrome.

Speaker
Keiko Yoshimoto, Katsuya Suzuki, Yumi Ikeda, Eriko Takei, Tsutomu Takeuchi
Conference Title
[Conference Category International presentation] Conference Title APLAR 2021 Dates 2021.08.28 - 2021.08.28
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Oral presentation (general)

The crosstalk between BAFF-signaling and sodium channel is involved in activation of monocytes of patients with primary Sjogren’s syndrome.

Speaker
Keiko Yoshimoto, Katsuya Suzuki, Yumi Ikeda, Eriko Takei, Tsutomu Takeuchi
Conference Title
[Conference Category Domestic presentation] Dates 2021.04 - 2021.04
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
Conference Category
Oral presentation (general)

Possible involvement of Fractalkine/CX3CR1 axis in peripheral CD14++CD16+ monocytes in disease development of patients with systemic lupus erythematosus.

Speaker
Keiko Yoshimoto, Katsuya Suzuki, Noriyasu Seki, Shuntaro Saito, Jun Kikuchi, Tsutomu Takeuchi
Conference Title
[Conference Category International presentation] Conference Title ACR 2020 Dates 2020.11 - 2020.11
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Oral presentation (general)

Elevated expression of BAFF receptor, BR3, in peripheral monocytes is involved in B cell activation and clinical features of patients with primary Sjögren’s syndrome.

Speaker
Keiko Yoshimoto, Katsuya Suzuki, Eriko Takei, Yumi Ikeda, Tsutomu Takeuchi
Conference Title
[Conference Category Domestic presentation] Dates 2020.08 - 2020.08
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
Japanese
Conference Category
Oral presentation (general)

Elevated expression of BAFF-receptor in peripheral monocytes promotes B cell activation and correlates with clinical manifestations of primary Sjogren’s syndrome.

Speaker
Keiko Yoshimoto, Katsuya Suzuki, Yumi Ikeda, Eriko Takei, Tsutomu Takeuchi
Conference Title
[Conference Category International presentation] Conference Title EULAR 2019 Dates 2019.06 - 2019.06
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Oral presentation (general)

Innovative drug discovery for autoimmune diseases aiming at BAFF signaling pathway.

Speaker
Keiko Yoshimoto, Katsuya Suzuki, Noriyasu Seki, Kunio Sugahara, Kenji Chiba, Tsutomu Takeuchi
Conference Title
[Conference Category International presentation] Conference Title Immunology 2019 Dates 2019.05 - 2019.05
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Oral presentation (general)

Elevated expression levels of the voltage-gated sodium channel 1.7 and BAFF receptor in peripheral monocytes contribute to activation of monocytes of patients with primary Sjögren’s syndrome.

Speaker
Keiko Yoshimoto, Yumi Ikeda, Katsuya Suzuki, Tsutomu Takeuchi
Conference Title
[Conference Category International presentation] Conference Title Immunology 2019(Venue San Diego, California, U.S.A.) Dates 2019.05 - 2019.05
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation

A low molecular weight BAFF signaling inhibitor reduces production of autoantibody and suppresses infiltration of B cells into the organs in autoimmune model mice.

Speaker
Keiko Yoshimoto, Katsuya Suzuki, Noriyasu Seki, Kunio Sugahara, Kenji Chiba, Tsutomu Takeuchi
Conference Title
[Conference Category Domestic presentation] Conference Title The 47th annual meeting of Japanese Society for Immunology Dates 2018.12 - 2018.12
Invitation Status
Without
Presentation Format
Domestic presentation
Language of Publication
English
Conference Category
Oral presentation (general)

Reduced expression of CX3CR1 in peripheral CD14++CD16+ monocytes is a novel feature of patients with systemic lupus erythematosus.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title ACR/ARHP Annual Meeting 2018 Dates 2018.10.22 - 2018.10.22
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation

Localization of the voltage-gated sodium channel 1.7 in peripheral monocytes contributes to activation of BAFF signaling in monocytes of patients with primary Sjögren’s syndrome.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title ACR/ARHP Annual Meeting 2018 Dates 2018.10.21 - 2018.10.21
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Oral presentation (general)

BAFFシグナルを標的とした低分子化合物を用いたシェーグレン症候群治療薬創製への試み

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category Domestic presentation] Dates 2018.09.14 - 2018.09.14
Invitation Status
With
Presentation Format
Domestic presentation
Language of Publication
Japanese
Conference Category
Symposium, workshop panel (nominated)

Possible involvement of BAFF and matrixmetalloproteinase-9 in the activation of monocytes of patients with primary Sjögren’s syndrome.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title EULAR 2018 Dates 2018.06.15 - 2018.06.15
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation

Elevated reactivity of CD38highIgD+ B cells against BAFF contributes to IgG overproduction in patients with primary Sjögren’s syndrome.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title EULAR 2018 Dates 2018.06.14 - 2018.06.14
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation

A low molecular weight BAFF signaling inhibitor, BIK-13, ameliorates B cell activation in vitro and in vivo autoimmune models and consequently suppresses production of IgG and cytokines.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title EULAR 2018 Dates 2018.06.13 - 2018.06.13
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Oral presentation (general)

A Low molecular weight BAFF receptor antagonist inhibits differentiation of human peripheral B cells into plasma blasts/plasma cells in vitro.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title IMMUNOLOGY 2018 Dates 2018.05.07 - 2018.05.07
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation

Low molecular weight BAFF receptor antagonists restrain infiltration of B cells into organs of autoimmune model mice by suppressing B cell activation.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title ACR/ARHP Annual Meeting 2017 Dates 2017.11 - 2017.11
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation

Inhibition of BAFF binding to its receptor, BR3, with low molecular weight compounds results in suppression of activation of monocytes and B cells in vitro and in vivo model of autoimmune diseases.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title IMMUNOLOGY 2017 Dates 2017.05 - 2017.05
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation

BAFF receptor antagonists suppress differentiation of B cells in vitro and are drug candidates for primary Sjögren’s syndrome.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title ACR/ARHP Annual Meeting 2016 Dates 2016.11 - 2016.11
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation

Low molecular weight compounds which inhibit BAFF binding to its receptor, BR3, suppress activation of monocytes.

Speaker
Yoshimoto Keiko
Conference Title
[Conference Category International presentation] Conference Title IMMUNOLOGY 2016 Dates 2016.05 - 2016.05
Invitation Status
Without
Presentation Format
International presentation
Language of Publication
English
Conference Category
Poster presentation