This center was the first at a private university to be designated as a WPI center, and it is Japan’s first microbiome research center. We will elucidate the interactions between the microbiome and humans at the molecular level. To this end, Bio2Q(World Premier International Research Center-WPI) brings together world leaders in microbiome research, organoid technology, metabolome analysis, neural circuit analysis, and quantum computation. It promotes cross-core collaborative research, leveraging cutting-edge technologies within its three research cores: the Human Multi-Organ Multi-Dimensional Data Analysis Core, the Multi-Organ Circulation Mechanism Analysis Core, and the Quantum Computing Core. Furthermore, through the establishment of a cross-disciplinary English program by the three Graduate Schools of Medicine, Pharmaceutical Sciences, and Science and Technology, as well as through inter-core mentoring, we aim to cultivate human resources who will be pivotal in advancing this collaborative research.