Keio University

Development of a New Nonlinear Raman Spectroscopy Method Using a Twin-Beam Light Source—Toward a Low-Cost, Compact, High-Resolution Raman Measurement Device—

Publish: June 09, 2025
Public Relations Office

June 9, 2025

Kyoto University

Keio University

Japan Science and Technology Agency

A research group led by Associate Professor Yujiro Eto of the Graduate School of Engineering, Kyoto University (at the time of the research, currently of the Graduate School of Science, Kyoto University), Associate Professor Mutsumi Tsuruya of the School of Medicine, Keio University, and Professor Hideaki Kano of the Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, has successfully performed nonlinear Raman spectroscopy by spectral focusing using a single nanosecond-pumped twin-beam light source. This technique conventionally required multiple expensive femtosecond ultrashort pulse light sources. This achievement presents a new measurement method using quantum light source technology, which is advancing toward practical application, and is expected to lead to the development of low-cost, compact, and high-performance next-generation molecular structure analysis devices.

This research was published online in the international academic journal Physical Review Applied on June 6, 2025.

Please see below for the full press release.

Press Release (PDF)