Keio University

Generation of Microgel Particles from an Ultra-High Viscosity Pre-gel Solution by Fusing Ultrasonic Irradiation Technology with Centrifugation

Publish: June 04, 2025
Public Relations Office

June 4, 2025

Tokyo University of Agriculture and Technology

Keio University

Mr. Yuta Bando of the Department of Mechanical Systems Engineering, Graduate School of Engineering, Tokyo University of Agriculture and Technology; Associate Professor Yuta Kurashina and Professor Yoshiyuki Tagawa of the Division of Advanced Mechanical Systems Engineering, Institute of Engineering at the same university; and Professor Hiroaki Onoe of the Department of Mechanical Engineering, Faculty of Science and Technology, Keio University, have developed a technology that fuses ultrasonic vibration with a technique for generating micro-sized droplets using centrifugal force. This technology enables the ejection of an ultra-high viscosity pre-gel solution—with a viscosity over 100 times greater than conventional solutions—from a microtube, successfully producing high-concentration microgel particles that were previously difficult to generate. This achievement is expected to contribute to future drug discovery research and regenerative medicine through drug delivery and cell culture using microgel particles.

Please see below for the full press release.

Press Release (PDF)