February 17, 2022
Okayama University
Keio University
ARAYA Inc.
A joint research group, including Associate Professor Teppei Matsui from the Graduate School of Natural Science and Technology (Faculty of Science, Biology) at Okayama University, Project Assistant Professor Trung Quang Pham from the National Institute for Physiological Sciences, Associate Professor Koji Jimura from the Faculty of Science and Technology at Keio University, and Principal Investigator Junichi Chikazoe from ARAYA Inc., has made a discovery that overturns a widely held theory about the brain's default mode using statistical modeling of brain activity.
These research findings are scheduled to be published as a Research Article in the American neuroscience journal Neuroimage on April 1 (already available in the online version).
The human brain exhibits vigorous activity even when at rest, a state known as the brain's default mode. In this study, the researchers used statistical modeling to examine a method widely used for analyzing the brain's default mode and discovered its problems. The results revealed that the widely held theory—that the brain's default state is composed of multiple stable states—may be incorrect.
These findings are expected to be a crucial starting point for applying the brain's default mode to the diagnosis of dementia and neuropsychiatric disorders.
Please see below for the full press release.