Keio University

Successful Deciphering of the Complete Genome Sequences of the Cynomolgus Monkey and Common Marmoset—Accelerating Drug Development Using Primates—

Publish: June 30, 2021
Public Relations Office

2021/06/30

Keio University

RIKEN

Tokyo Metropolitan Institute of Medical Science

Shiga University of Medical Science

Central Institute for Experimental Animals

Japan Agency for Medical Research and Development

A joint research group led by Professor Yasubumi Sakakibara of the Faculty of Science and Technology, Keio University; Deputy Program Director Jun Kawai of the RIKEN Program for Drug Discovery and Medical Technology Platforms; Team Leader Kiyonori Kugoh of the RIKEN Center for Biosystems Dynamics Research; Deputy Director Hideya Kawaji of the Tokyo Metropolitan Institute of Medical Science; Professor Masatsugu Ema of the Center for Animal Life Science, Shiga University of Medical Science; and Department Head Erika Sasaki of the Department of Marmoset Medical Biology, Central Institute for Experimental Animals, has successfully deciphered the complete genome sequences of the cynomolgus monkey and the common marmoset, which are non-human primate model animals used in drug discovery research, to a near-complete, chromosome-level. The cynomolgus monkey, a primate like humans, is actively studied due to its importance as a preclinical experimental model animal used in drug development. The results of this genome sequencing will establish a genomic information infrastructure for the cynomolgus monkey and marmoset, facilitating the evaluation of efficacy and the prediction and interpretation of safety in drug discovery research, and is expected to lead to new innovations in drug discovery. The results of this research were published in the international journal “Scientific Data” on June 28, 2021.

Please see below for the full press release.

Press Release (PDF)