11/24/2020
National Cerebral and Cardiovascular Center
Osaka University
Keio University School of Medicine
A research team led by Dr. Satoshi Hosoki (a fourth-year student in the Doctoral Programs at the Keio University Graduate School of Medicine), Dr. Satoshi Saito, and Dr. Masafumi Ihara of the Department of Neurology at the National Cerebral and Cardiovascular Center (NCVC; Suita, Osaka; President: Hisao Ogawa), in collaboration with an international research group including Associate Professor Ryota Nomura and Professor Kazuhiko Nakano of the Department of Oral Molecular Microbiology, Osaka University Graduate School of Dentistry, Professor Jin Nakahara of the Department of Neurology, Keio University School of Medicine, and Professor Emeritus Norihiro Suzuki, has revealed that among the bacteria that cause dental caries (so-called Streptococcus mutans), the cnm-gene-positive strain (cnm-positive S. mutans), which can bind to collagen in cerebral blood vessels, is involved in the development of cerebral microbleeds. The results of this study were published in the December 2020 issue of Stroke, an international journal published by the American Heart Association and the American Stroke Association, and were featured on the cover of the issue.
For the full press release, please see below.